SKIN-CAD® Version 6.0
SKIN-CAD brochure English-version (SKIN-CAD_E.pdf, PDF - 664KB)
New Features in Version 6.0
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Addition of in vitro release data analysis |
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Addition of Freundlich-type binding scheme to skin permeation model |
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Addition of indirect response model to PK-PD model |
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Addition of automatic searching function of steady-state profile to in
vitro skin permeation data analysis |
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Improvement of GUI |
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Improvement of deconvolution program for blood concentration data analysis |
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Addition of literature data to parameters list |
SKIN-CAD Overview
SKIN-CAD is a general simulation software for the skin and body pharmacokinetics
following transdermal and topical drug delivery. SKIN-CAD predicts dynamic
profiles of skin permeation and distribution and blood concentration under
various modes of transdermal delivery. SKIN-CAD also analyzes the effects
of metabolism and binding in the skin, dermal blood uptake, iontophoresis,
and so on.
SKIN-CAD Utilization
SKIN-CAD can be used for optimizing the design of transdermal drug delivery
systems (prediction of clinical performance, setup of administration schedule)
as well as for evaluating the effects of various factors on skin permeation
and blood concentration profiles. With the model parameters determined
from in vitro or in vivo experiments or evaluated from correlation equations,
SKIN-CAD can quickly provide you with graphical images; blood concentration
- time profile for systemic application, drug distribution in the skin
for topical application, skin permeability of skin-care products.
SKIN-CAD provides in vivo/in vitro/in silico pharmacokinetic evaluation for optimal design of transdermal drug delivery systems.
System requirements
| OS |
Windows 98, Me, 2000, XP*, Vista* (excluding 64-bit edition) |
| CPU |
Intel Pentium 133MHz processor (much faster recommended) |
| Display |
800 x 600 screen resolution (1024 x 768 or higher recommended) |
| Hard disk |
20MB of available space |
| Memory |
64MB of RAM (128MB or larger recommended) |
| CD-ROM drive |
Required for installation |
| Browser |
Required for online help (Firefox, IE, NN, etc.) |
Partnership
| General editor |
Kakuji Tojo, Ph.D., Professor, Kyushu Institute of Technology |
| Distributing agents |
INFOCOM CORPORATION (Chem&Bio-informatics Department)
Fujitsu Kyushu Systems Ltd. (Life Science Systems Department) |
Development history
| July, 2009 |
Version 6.0 release |
| Dec., 2008 |
Version 5.2 release |
| May, 2007 |
Version 5.1 release |
| June, 2006 |
Professional Edition Version 5.0 release |
| Dec., 2005 |
Professional Edition Version 4.1 release |
| June, 2004 |
Professional Edition Version 4.0 release |
| May, 2003 |
Professional Edition Version 3.0 release |
| Apr., 2002 |
Professional Edition Version 2.0 release |
| Aug., 2001 |
Foundation of Biocom Systems, Inc. |
| Apr., 2001 |
Professional Edition Version 1.1 release |
| Sep., 2000 |
Professional Edition Version 1.0 release |
| May, 1999 |
Start of developing SKIN-CAD for Windows |
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| For customers |
Please contact us if you have any questions and comments. |
| General editor |
Kakuji Tojo, Ph.D., Professor
(Kyushu Institute of Technology) |
| SKIN-CAD is a registered trademark of Biocom Systems, Inc. in Japan. |
| Users |
Japanese pharmaceutical companies
Foreign pharmaceutical companies
University of Oxford
Loughborough University |
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